What would happen if…? Thoughts (and thought experiments) on the calorie issue

Thought experiments are devices of the imagination used to investigate the nature of things…. The primary philosophical challenge of thought experiments is simple: How can we learn about reality (if we can at all), just by thinking? More precisely, are there thought experiments that enable us to acquire new knowledge about the intended realm of investigation … [Read more]

The Launch of The Nutrition Science Initiative

0 NuSI image

This morning, at 9am Eastern Time, we officially launched The Nutrition Science Initiative — NuSI (pronounced “new see”). NuSI is a non-profit organization, technically a 501(c)(3). Its purpose  is to facilitate and fund rigorous, well-controlled experiments targeted at resolving unambiguously many of the outstanding nutrition controversies — to answer the question definitively of what constitutes … [Read more]

Metabolism, Diet, and Disease Conference update and a job posting

  I promised in my last post — yes, far too long ago — that I would give an update on the Metabolism, Diet and Disease Conference, which was held at the end of May in Washington, DC. As the months passed, I was waiting to hear from the organizers that they had posted a … [Read more]

Metabolism, Diet, and Disease Conference

Well, it’s  Back to the Better-Late-Than-Never… There’s an interesting conference starting Tuesday the 29th in Washington – today –and I should have written about it months ago. It’s the Metabolism, Diet and Disease conference being held at the Georgetown University Conference Center. The editors of BioMed Central, a British open-access science publishing company, are the organizers. … [Read more]

Science, Pseudoscience, Nutritional Epidemiology, and Meat

  I’m writing this post with a little more haste than is my wont. I’ve received dozens of e-mails asking me to comment on the recent news — ala the the New York Times — that meat-eating apparently causes premature death and disease. So this post is likely to contain more than my usual number of typos, egregious spelling … [Read more]

On the greatly-exaggerated demise of the insulin-hypothesis


Last week, I tweeted a New England Journal of Medicine image challenge, part of the journal’s continuing education program for physicians. I suggested that it might be a source of comfort to those who were worried about the insulin hypothesis as a viable hypothesis to explain obesity and excess fat accumulation. Although I linked to … [Read more]